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Lockhart A, Reed A, Rezende de Castro T, Herman C, Campos Canesso MC, Mucida D. Dietary protein shapes the profile and repertoire of intestinal CD4+ T cells. J Exp Med. 2023 Aug 7. doi: 10.1084/jem.20221816 PMID: 37191720 

Reis BS, Darcy PW, Khan IZ, Moon CS, Kornberg AE, Schneider VS, Alvarez Y, Eleso O, Zhu C, Schernthanner M, Lockhart A. TCR-Vγδ usage distinguishes protumor from antitumor intestinal γδ T cell subsets. Science. 2022 Jul 14. doi: 10.1126/science.abj8695 PMID: 35857588

Parsa R, London M, Rezende de Castro TB, Reis B, Buissant des Amorie J, Smith JG, Mucida D. Newly recruited intraepithelial Ly6A⁺ CCR9⁺ CD4⁺ T cells protect against enteric viral infection. Immunity. 2022 May 19. doi: 10.1016/j.immuni.2022.05.00. PMID: 35617965

Ahrends T, Aydin B, Matheis F, Classon CH, Marchildon F, Furtado GC, Lira SA, Mucida D. Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections. Cell. 2021 Nov 11;184(23):5715-5727.e12. doi:10.1016/j.cell.2021.10.004. Epub 2021 Oct 29. PMID: 34717799; PMCID: PMC8595755.

London M, Bilate AM, Castro TBR, Sujino T, Mucida D. Stepwise chromatin and transcriptional acquisition of an intraepithelial lymphocyte program. Nat Immunol. 2021 Apr;22(4):449-459. doi: 10.1038/s41590-021-00883-8. Epub 2021 Mar 8. PMID: 33686285; PMCID: PMC8251700.

Nowosad CR, Mesin L, Castro TBR, Wichmann C, Donaldson GP, Araki T, Schiepers A, Lockhart AAK, Bilate AM, Mucida D, Victora GD. Tunable dynamics of B cellselection in gut germinal centres. Nature. 2020 Dec;588(7837):321-326. doi:10.1038/s41586-020-2865-9. Epub 2020 Oct 28. PMID: 33116306; PMCID: PMC7726069.

Bilate AM, London M, Castro TBR, Mesin L, Bortolatto J, Kongthong S, HarnagelA, Victora GD, Mucida D. T Cell Receptor Is Required for Differentiation, but Not Maintenance of Intestinal CD4⁺ Intraepitelial Lymphocytes. Immunity. 2020 Nov 17;53(5):1001-1014.e20. doi: 10.1016/j.immuni.2020.09.003. Epub 2020 Oct 5. PMID: 33022229; PMCID: PMC7677182.

Muller PA, Matheis F, Schneeberger M, Kerner Z, Jové V, Mucida D. Microbiota-modulated CART⁺ enteric neurons autonomously regulate blood glucose. Science. 2020 Oct 16;370(6514):314-321. doi: 10.1126/science.abd6176. Epub 2020Aug 27. PMID: 32855216; PMCID: PMC7886298.

Muller PA, Schneeberger M, Matheis F, Wang P, Kerner Z, Ilanges A,Pellegrino K, Del Mármol J, Castro TBR, Furuichi M, Perkins M, Han W, Rao A,Pickard AJ, Cross JR, Honda K, de Araujo I, Mucida D. Microbiota modulate sympathetic neurons via a gut-brain circuit. Nature. 2020 Jul;583(7816):441-446.doi: 10.1038/s41586-020-2474-7. Epub 2020 Jul 8. Erratum in: Nature. 2020Sep;585(7823):E2. PMID: 32641826; PMCID: PMC7367767.

Matheis F, Muller PA, Graves CL, Gabanyi I, Kerner ZJ, Costa-Borges D,Ahrends T, Rosenstiel P, Mucida D. Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss. Cell. 2020 Jan 9;180(1):64-78.e16. doi: 10.1016/j.cell.2019.12.002. PMID: 31923400; PMCID: PMC7271821.

Esterházy D, Canesso MCC, Mesin L, Muller PA, de Castro TBR, Lockhart A,ElJalby M, Faria AMC, Mucida D. Compartmentalized gut lymph node drainage dictates adaptive immune responses. Nature. 2019 May;569(7754):126-130. doi:10.1038/s41586-019-1125-3. Epub 2019 Apr 15. PMID: 30988509; PMCID: PMC6587593.

Hoytema van Konijnenburg DP, Reis BS, Pedicord VA, Farache J, Victora GD,Mucida D. Intestinal Epithelial and Intraepithelial T Cell Crosstalk Mediates a Dynamic Response to Infection. Cell. 2017 Nov 2;171(4):783-794.e13. doi:10.1016/j.cell.2017.08.046. Epub 2017 Sep 21. PMID: 28942917; PMCID: PMC5670000.

Pedicord VA, Lockhart AAK, Rangan KJ, Craig JW, Loschko J, Rogoz A, Hang HC,Mucida D. Exploiting a host-commensal interaction to promote intestinal barrier function and enteric pathogen tolerance. Sci Immunol. 2016 Sep;1(3):eaai7732.doi: 10.1126/sciimmunol.aai7732. Epub 2016 Sep 22. PMID: 28580440; PMCID:PMC5453653.

Sujino T, London M, Hoytema van Konijnenburg DP, Rendon T, Buch T, Silva HM,Lafaille JJ, Reis BS, Mucida D. Tissue adaptation of regulatory andintraepithelial CD4⁺ T cells controls gut inflammation. Science. 2016 Jun24;352(6293):1581-6. doi: 10.1126/science.aaf3892. Epub 2016 Jun 2. PMID:27256884; PMCID: PMC4968079.

Esterházy D, Loschko J, London M, Jove V, Oliveira TY, Mucida D. Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance. Nat Immunol. 2016 May;17(5):545-55. doi:10.1038/ni.3408. Epub 2016 Mar 28. PMID: 27019226; PMCID: PMC4837106.

Gabanyi I, Muller PA, Feighery L, Oliveira TY, Costa-Pinto FA, Mucida D.Neuro-immune Interactions Drive Tissue Programming in Intestinal Macrophages. Cell. 2016 Jan 28;164(3):378-91. doi: 10.1016/j.cell.2015.12.023. Epub 2016 Jan14. PMID: 26777404; PMCID: PMC4733406.

Reis BS, Lee K, Fanok MH, Mascaraque C, Amoury M, Cohn LB, Rogoz A, DallnerOS, Moraes-Vieira PM, Domingos AI, Mucida D. Leptin receptor signaling in T cells is required for Th17 differentiation. J Immunol. 2015 Jun1;194(11):5253-60. doi: 10.4049/jimmunol.1402996. Epub 2015 Apr 27. PMID:25917102; PMCID: PMC4433844.

Rogoz A, Reis BS, Karssemeijer RA, Mucida D. A 3-D enteroid-based model to study T-cell and epithelial cell interaction. J Immunol Methods. 2015Jun;421:89-95. doi: 10.1016/j.jim.2015.03.014. Epub 2015 Apr 2. PMID: 25841547;PMCID: PMC4451438.

Reis BS, Hoytema van Konijnenburg DP, Grivennikov SI, Mucida D. Transcription factor T-bet regulates intraepithelial lymphocyte functional maturation. Immunity. 2014 Aug 21;41(2):244-56. doi:10.1016/j.immuni.2014.06.017. PMID: 25148025; PMCID: PMC4287410.

Reis BS, Rogoz A, Costa-Pinto FA, Taniuchi I, Mucida D. Mutual expression ofthe transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cellimmunity. Nat Immunol. 2013 Mar;14(3):271-80. doi: 10.1038/ni.2518. Epub 2013Jan 20. PMID: 23334789; PMCID: PMC3804366.

For a full list of publications, see PubMed.

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